Reading Time: 2 minutesBiomarkers in Oxford (BioMOx) is a research project with the aim of identifying a diagnostic biomarker for MND, which could be used to track the
Tag: Project a day
Reading Time: 2 minutesInduced pluripotent stem cell (iPSC) technology has enabled researchers to create and study living human motor neurones in the lab, derived originally from patient skin
Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse
Reading Time: 2 minutesA team at the Sheffield Institute for Translational Neuroscience are creating a zebrafish model to study the C9orf72 gene mutation in MND, and work out
Reading Time: 2 minutesPrevious research in humans and zebrafish has shown that before symptoms arise in MND, early changes occur in the interneurones. This type of nerve cell
Reading Time: 2 minutesDuring the early stages of MND it is proposed that motor neurones are more susceptible to an imbalance of oxygen within the cells, known as
Reading Time: 2 minutesIf you looked at the motor neurones of people with MND down the microscope you would see clumps of a protein called TDP-43. Researchers around
Reading Time: 2 minutesDeveloping disease models is important for furthering our understanding of MND and allows researchers to screen potential new drugs for a beneficial effect. Moving a
Reading Time: 2 minutesDeposits of the protein TDP-43 are found within the motor neurones in the majority of cases of MND, and are considered a pathological hallmark of