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Students support MND research awareness with a conference

Students support MND research awareness with a conference

Reading Time: 5 minutes Soon after 8 medical students at the University of Southampton volunteered for the Motor Neurone Disease Association (with their local Southampton and Winchester branch) and created an MND Association MedSoc group at the University, they decided to organise an MND conference in February 2020 to raise interest amongst medical students and other healthcare professionals. Among…

TUDCA-ALS has started recruiting in the UK

TUDCA-ALS has started recruiting in the UK

Reading Time: 3 minutes TUDCA-ALS is a European Consortium (funded by the European Commission under the Horizon 2020 grant) involving top researchers from seven countries across Europe (see Figure 1). The Consortium aims to find a new treatment to slow down the progression of MND/ALS by conducting a clinical trial to investigate the safety and efficacy (effectiveness) of Tauroursodeoxycholic…

Focusing on mitochondria – a potential target for early MND treatment?

Focusing on mitochondria – a potential target for early MND treatment?

Reading Time: 3 minutes Dr Arpan Mehta, one of our Lady Edith Wolfson Clinical Fellows, and his team at the Euan MacDonald Centre at the University of Edinburgh have recently carried out a systematic review and meta-analysis of the pre-clinical literature (studies using animal models) to assess the therapeutic potential of targeting mitochondrial dysfunction in MND, examining if these…

How animals are helping to improve our understanding of MND

How animals are helping to improve our understanding of MND

Reading Time: 6 minutes ‘From antibiotics and insulin to blood transfusions and treatments for cancer or HIV, virtually every medical achievement in the past century has depended directly or indirectly on research using animals’ – from the Royal Society’s position statement on the use of animals in research. We know that talking about using animals in research is an…

Tackling weight loss in MND – from ProGas to PostGas

Reading Time: 2 minutes Swallowing problems are an incredibly common cause of malnutrition and weight loss in MND patients. To add to this, weight loss in MND is associated with shorter survival. This means managing swallowing problems effectively is crucial to ensuring people living with MND can have the best possible quality of life. Managing swallowing problems using gastrostomy…

Lighthouse Project shines a beacon on HERVs and their role in ALS

Reading Time: 3 minutes There is recent evidence to suggest that Human Endogenous Retroviruses (HERVs) may be involved in amyotrophic lateral sclerosis (ALS). HERV-K has been directly linked to motor neurone damage and has been found in the brain tissue of patients with ALS. The MND Association recently awarded a small grant to fund part of the ‘Lighthouse Project’…