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Does the glymphatic system play a role in MND?

Does the glymphatic system play a role in MND?

Reading Time: 3 minutes At last year’s International Symposium on ALS/MND in Perth, Australia, Professor Jeffrey Iliff talked about the glymphatic system (C1 in abstract book) – a series of ‘tunnels’ containing cerebrospinal fluid (CSF) that distributes nutrients and removes waste from the central nervous system. Prof. Iliff’s team demonstrated that the glymphatic system fails both in the ageing…

Studentship success – next steps for Matthew Nolan

Studentship success – next steps for Matthew Nolan

Reading Time: 5 minutes Guest researcher blog post written by Matthew Nolan. My name is Matthew, I’m currently a post-doctoral researcher at Massachusetts General Hospital and Harvard Medical School in the USA, supported by a Cullen Education and Research Young Investigator Award. Last year I finished my MND Association-funded PhD at the University of Oxford, where I was supervised by…

Toxicity of cerebrospinal fluid in ALS/MND

Toxicity of cerebrospinal fluid in ALS/MND

Reading Time: 4 minutes A systematic review of existing scientific literature, performed by a team of researchers led by Dr Arpan Mehta, MRC/MND Association Lady Edith Wolfson Clinical Fellow based at the Euan MacDonald Centre, University of Edinburgh, supports the view that cerebrospinal fluid obtained from patients with ALS/MND is toxic to cells.  This finding could help to establish…

The FUS with faulty mitochondria – the powerhouse of the cell

The FUS with faulty mitochondria – the powerhouse of the cell

Reading Time: 3 minutes Guest researcher blog post written by Darija Šoltić. Originally from Croatia, I came to the UK to do my PhD in neuroscience, where I worked on spinal muscular atrophy, a debilitating childhood motor neuron disease (MND). Earlier this year, I joined the Ruepp group (led by Dr Marc-David Ruepp) at the UK Dementia Research Institute…

Panic at the (Cell’s) Depot

Panic at the (Cell’s) Depot

Reading Time: 5 minutes Guest researcher blog post written by Sam Bryce-Smith – sharing his research into changes in ‘post-code’ sequences of RNA, how it continues during the COVID-19 pandemic, and the importance of his funding. We are extremely grateful for the support of the London Freemasons, who are generously supporting one of our new PhD Studentships held by…

Highlighting MND researchers of the future – part 2

Highlighting MND researchers of the future – part 2

Reading Time: 4 minutes Last week saw the culmination of 12-months of planning as the 30th International Symposium on ALS/MND took place in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 100 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals…

Highlighting the MND researchers of the future – part 1

Highlighting the MND researchers of the future – part 1

Reading Time: 4 minutes This week sees the start of the 30th International Symposium on ALS/MND in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 110 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals to share new understanding of the…

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Reading Time: 3 minutes The Science Show on ABC Radio National in Australia, features an interview with Professor Justin Yerbury on Saturday 17th August. The article containing the interview titled ‘Resistant nerves could lead to treatment for neurodegenerative disease‘ is a fascinating insight into Prof Yerbury’s work on the  delicate balance of proteins in solution within our nerves and…