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Panic at the (Cell’s) Depot

Panic at the (Cell’s) Depot

Reading Time: 5 minutes Guest researcher blog post written by Sam Bryce-Smith – sharing his research into changes in ‘post-code’ sequences of RNA, how it continues during the COVID-19 pandemic, and the importance of his funding. We are extremely grateful for the support of the London Freemasons, who are generously supporting one of our new PhD Studentships held by…

Highlighting MND researchers of the future – part 2

Highlighting MND researchers of the future – part 2

Reading Time: 4 minutes Last week saw the culmination of 12-months of planning as the 30th International Symposium on ALS/MND took place in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 100 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals…

Highlighting the MND researchers of the future – part 1

Highlighting the MND researchers of the future – part 1

Reading Time: 4 minutes This week sees the start of the 30th International Symposium on ALS/MND in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 110 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals to share new understanding of the…

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Reading Time: 3 minutes The Science Show on ABC Radio National in Australia, features an interview with Professor Justin Yerbury on Saturday 17th August. The article containing the interview titled ‘Resistant nerves could lead to treatment for neurodegenerative disease‘ is a fascinating insight into Prof Yerbury’s work on the  delicate balance of proteins in solution within our nerves and…

Focusing on mitochondria – a potential target for early MND treatment?

Focusing on mitochondria – a potential target for early MND treatment?

Reading Time: 3 minutes Dr Arpan Mehta, one of our Lady Edith Wolfson Clinical Fellows, and his team at the Euan MacDonald Centre at the University of Edinburgh have recently carried out a systematic review and meta-analysis of the pre-clinical literature (studies using animal models) to assess the therapeutic potential of targeting mitochondrial dysfunction in MND, examining if these…

Could MND be treated by HIV drugs?

Could MND be treated by HIV drugs?

Reading Time: 4 minutes Recently published results from the open-label Lighthouse trial investigating safety of the drug Triumeq in people with MND revealed the treatment was safe and ready to progress to a larger Phase 3 clinical trial. The trial was held in Australia and recruited 40 people with MND who all received the active drug; this was because…

How animals are helping to improve our understanding of MND

How animals are helping to improve our understanding of MND

Reading Time: 6 minutes ‘From antibiotics and insulin to blood transfusions and treatments for cancer or HIV, virtually every medical achievement in the past century has depended directly or indirectly on research using animals’ – from the Royal Society’s position statement on the use of animals in research. We know that talking about using animals in research is an…

FaTHoM 2: UK-leading MND clinicians on inherited MND

FaTHoM 2: UK-leading MND clinicians on inherited MND

Reading Time: 4 minutes After its successful premiere in 2017, the University of Oxford organised another meeting of people affected by inherited MND, called ‘Families for the Treatment of Hereditary MND (FaTHoM)’. This turned out to be yet another excellent day where MND clinicians-researchers presented on topics such as genetics of MND, genetic testing and gene therapies. Below you…