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18 May 2023
Does MND share genes with other neurodegenerative…
2 May 2023
DAZALS: A new clinical trial for MND
26 April 2023
What does the FDA approval of Tofersen…
Person writing in a notepad by a laptop
20 April 2023
Measuring cognitive and behavioural changes in MND
A researchers hands working on cell culture
31 March 2023
Are there differences between male and female…
Nasal spray bottle spraying medicine
24 March 2023
Behind the headlines: could a potential treatment…
16 March 2023
The DiAMoND Study: a new decision aid…
9 March 2023
One hundred not out: keeping up the…
MAGNET: A new MND clinical platform trial now recruiting in the UK

MAGNET: A new MND clinical platform trial now recruiting in the UK

Reading Time: 5 minutes The pace of MND research continues to increase, with more clinical trials underway in the UK, over the last year, than ever before. Adding to this momentum, the clinical platform trial MAGNET (Multi-arm, Adaptive, Group-sequential trial NETwork)has just opened to recruitment in the UK.

Over the last several decades, there have been over 140 clinical trials for MND and unfortunately most of these have not led to effective treatments. More recently, clinical trial design has become more innovative, including the use of platform trials. MAGNET is a platform trial which aims to accelerate the development of new potential treatments for MND by testing multiple drugs simultaneously.

Behind the headlines: could a potential treatment for MND be developed into a nasal spray?

Behind the headlines: could a potential treatment for MND be developed into a nasal spray?

Reading Time: 6 minutes Recent research, led by Professor Guillaume Hautbergue at the University of Sheffield, has found a potential new method of preventing nerve cell death in the most common genetic form of MND. This new method could, with further studies, lead to the development of a potential therapy for C9orf72 MND, and a type of dementia called…

The DiAMoND Study: a new decision aid for people with MND

The DiAMoND Study: a new decision aid for people with MND

Reading Time: 4 minutes Some people with MND experience severe swallowing difficulties and it is estimated that over 50% of those with MND are affected by malnutrition and weight loss due to this. These factors are thought to be associated with increased disability and shortened survival, which is why nutrition remains one of the main challenges surrounding disease management. For those with MND who have severe swallowing difficulties, one of the long-term nutritional support options is a gastrostomy (a feeding tube that is inserted directly into the stomach to deliver food, fluids and some medications).