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Boosting energy in nerve cells is a promising target for MND treatments

Boosting energy in nerve cells is a promising target for MND treatments

Reading Time: 3 minutes A study conducted by researchers at the Euan MacDonald Centre at the University of Edinburgh has shed light on how improving the function of mitochondria – the power supply of nerve cells – could be a potential treatment for motor neurone disease, paper published this week in the journal, Acta Neuropathologica (2021). This study paves…

Virtual Symposium: Through the eyes of an early career MND researcher

Virtual Symposium: Through the eyes of an early career MND researcher

Reading Time: 4 minutes This blog is part of the ‘Virtual Highlights’ collection of articles, where you can read about the content of some of the talks and posters presented at the Virtual 31st International Symposium on ALS/MND. Guest researcher blog post written by Nora Markus, 2019 Symposium Biomedical Poster Prize winner. About me My name is Nora Markus,…

SPiQE – new analytical tool digs deeper into fasciculations

SPiQE – new analytical tool digs deeper into fasciculations

Reading Time: 5 minutes Cristina Cabassi is an honorary research assistant investigating fasciculations in people with MND. In this guest blog she tells us a little about herself and the project she is involved with – SPiQE, which stands for surface potential quantification engine, technology developed to detect activity from a specific type of muscle recording.

Update on the CENTAUR trial: open label extension data

Update on the CENTAUR trial: open label extension data

Reading Time: 3 minutes A centaur was a creature from Greek mythology which was half-man and half-horse. Despite such an unusual appearance such a combination could have its advantages. It seems that another combination may hold promise in the future for people with ALS/MND (see our previous blog). The CENTAUR clinical trial, which tested a combination of two compounds,…

Understanding family experiences of inherited MND: developing a new web resource on Healthtalk.org

Understanding family experiences of inherited MND: developing a new web resource on Healthtalk.org

Reading Time: 4 minutes Guest researcher blog post written by Jade Howard. Hello, my name is Jade Howard and I am a second year PhD student from The Health Services Research Unit at the University of Aberdeen. I am working on a study of families’ experiences of inherited forms of MND, which affect around 5-10% of people with the…

Does the glymphatic system play a role in MND?

Does the glymphatic system play a role in MND?

Reading Time: 3 minutes At last year’s International Symposium on ALS/MND in Perth, Australia, Professor Jeffrey Iliff talked about the glymphatic system (C1 in abstract book) – a series of ‘tunnels’ containing cerebrospinal fluid (CSF) that distributes nutrients and removes waste from the central nervous system. Prof. Iliff’s team demonstrated that the glymphatic system fails both in the ageing…