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Behind the headlines: could a potential treatment for MND be developed into a nasal spray?

Behind the headlines: could a potential treatment for MND be developed into a nasal spray?

Reading Time: 6 minutes Recent research, led by Professor Guillaume Hautbergue at the University of Sheffield, has found a potential new method of preventing nerve cell death in the most common genetic form of MND. This new method could, with further studies, lead to the development of a potential therapy for C9orf72 MND, and a type of dementia called…

Why is understanding hypermetabolism important in ALS outcomes?

Why is understanding hypermetabolism important in ALS outcomes?

Reading Time: 7 minutes Shyuan’s talk was titled ‘Investigating the role of hypermetabolism in ALS’ (C06 in the abstract book) and discussed the research being carried out by her team to try and understand the mechanisms driving hypermetabolism in ALS and what hypermetabolism means clinically for people living with the disease. This blog details Shyuan’s work and looks closely at her observations on hypermetabolism in relation to ALS.

Can signs of MND be detected before symptoms appear?

Can signs of MND be detected before symptoms appear?

Reading Time: 6 minutes It has been suggested that there might be a pre-symptomatic stage of MND, where the disease is active and occurring within a person but no symptoms are showing. There is currently little research in this area and a lack of evidence of a pre-symptomatic stage of the disease. However, if it can be shown that there is a pre-symptomatic stage which can be measured, this could be very useful in helping people with MND to get treatment as early as possible. Dr Michael Benatar, from the University of Miami, has been looking into this by studying the development of MND and how the disease presents in people who have a high risk of developing it.

Conversations with…4 international MND researchers

Conversations with…4 international MND researchers

Reading Time: 3 minutes Last week at the 33rd International Symposium on ALS/MND, we heard some exciting updates on a wide range of research happening all over the world. The pace of ALS/MND research has drastically increased over recent years and we now have a better understanding about the underlying biology of the disease which is crucial to being able to identify new potential drug targets.

Cells behaving badly: what’s going wrong in immune cells in MND?

Cells behaving badly: what’s going wrong in immune cells in MND?

Reading Time: 5 minutes A recent paper published in the Journal Neurology: Neuroimmunology & Neuroinflammation has revealed new insights into how immune cells behave in MND. This work, which is the result of a collaboration between researchers across different universities, aimed to uncover more about the role of the immune system in MND progression. The study used blood samples…