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Examining the effects of the compound NU-9 in MND mice

Examining the effects of the compound NU-9 in MND mice

Reading Time: 4 minutes A research paper published recently has investigated the effect of a compound called ‘NU-9’ in mice models of MND. Before we go on, it is important to define ‘compound’ in this context. A compound is something that has pharmacological or biological activity that is likely to be therapeutically useful. It serves as a starting point…

Flexible molecules and droplets: researching and targeting RNA-protein complexes in MND

Flexible molecules and droplets: researching and targeting RNA-protein complexes in MND

Reading Time: 6 minutes My name is Tatyana Shelkovnikova, I am an MND Association Lady Edith Wolfson Senior Non-Clinical fellow. I lead my own group at the Medicines Discovery Institute, Cardiff University. I chose to move my fellowship to a drug discovery unit with a strong neuroscience portfolio of projects to be able to stay at the frontier of…

Highlighting MND researchers of the future – part 2

Highlighting MND researchers of the future – part 2

Reading Time: 4 minutes Last week saw the culmination of 12-months of planning as the 30th International Symposium on ALS/MND took place in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 100 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals…

Highlighting the MND researchers of the future – part 1

Highlighting the MND researchers of the future – part 1

Reading Time: 4 minutes This week sees the start of the 30th International Symposium on ALS/MND in Perth, Australia. The Symposium brings together the brightest minds from the MND research and healthcare communities. With 110 oral presentations, and over 420 posters, the Symposium is an opportunity for around 1,000 researchers and healthcare professionals to share new understanding of the…

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Do the eyes have it? Could Resistant Nerves See Our Way to a Treatment?

Reading Time: 3 minutes The Science Show on ABC Radio National in Australia, features an interview with Professor Justin Yerbury on Saturday 17th August. The article containing the interview titled ‘Resistant nerves could lead to treatment for neurodegenerative disease‘ is a fascinating insight into Prof Yerbury’s work on the  delicate balance of proteins in solution within our nerves and…

What’s going on inside? Possible mechanisms associated with physical activity and MND

Reading Time: 5 minutes Physical activity and MND – part 3 This is the final blog article in our trio of blogs that are looking at physical activity and MND. The first two have addressed the questions ‘did the amount of physical activity I undertook before my diagnosis cause my MND?’ and ‘can I continue with physical activity after my…