Kate Bibbings is a PhD student funded by the MND Association, who is using ultrasound as a diagnostic tool for MND. Like Dr Martin Turner, she is hoping to speed up the diagnosis of MND. Based at Manchester Metropolitan University, here she gives us an introduction to her research.
B Mode ultrasound has been used a number of times to successfully identify muscle twitches. Recordings may be made of activity and movement within the selected muscle and analysed in order to determine the presence of muscle twitches. This has previously been done by individuals with experience in ultrasound video analysis and using the technique of manual identification/ classification. However, this is a subjective and time consuming technique.
The aim of this study is to evaluate the performance of previously developed automated ultrasound analysis techniques, whilst investigating improvements or alternatives that may be used for the automated detection of muscle twitches. This will be done with the scope to making a diagnosis of Motor Neurone Disease whilst blinded to the actual clinical diagnosis, using only ultrasound images and the automated twitch detection technique. This will enable the viability of using ultrasound as a clinical diagnostic technique to be assessed and compared to the current technique of intramuscular Electromyography.
Currently, work is being carried out into investigating the effects of probe orientation and positioning on image quality (determined by such features as fascicle definition). It is hoped that this work will pay dividends when we begin collecting our first pilot data at Royal Preston Hospital, late July 2014.
The Muscle Function Lab at Manchester Metropolitan University
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