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Year: 2016

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  • 2016
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Clinical Trials MND Research

ALS/MND Clinical Trial Guidelines: your opportunity to comment!

29 July 2016

Reading Time: 2 minutesA few months ago we wrote an article about the ALS Clinical Trials Workshop which took place in Virginia, USA. Since then the Guidelines Working

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Causes and disease mechanisms MND Research News Research we fund

New genetic discoveries tell us more about what causes MND – Part 2

27 July 2016

Reading Time: 2 minutesTwo sets of MND genetic results were published yesterday. One of these results was about the importance of a new gene called NEK1. The second

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Causes and disease mechanisms MND Research Research we fund

New genetic discoveries tell us more about what causes MND – Part 1

26 July 2016

Reading Time: 3 minutesToday some exciting news about the genetics of MND was published in the scientific journal Nature Genetics. The results come in two research papers published

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Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

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Causes and disease mechanisms MND Research Research we fund

Motor neurone signalling and the effects of RNA in MND

30 June 201629 April 2022

Reading Time: 2 minutesDr Pietro Fratta completed his first MRC-MND Association Clinical Research Training Fellowship in 2014. Last year he was awarded a new £1.16 million Clinician Scientist

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Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

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Causes and disease mechanisms MND Research Research we fund

Using iPSCs to understand why motor neurones lose their normal function in MND

28 June 20168 April 2022

Reading Time: 2 minutesResearchers can create human motor neurones exhibiting signs of MND in the lab by taking skin cells from a person living with MND and reprogramming

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Causes and disease mechanisms MND Research Research we fund

Transforming skin cells into nerve cells to understand MND gene mutations

27 June 201629 April 2022

Reading Time: 2 minutesIn previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human

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Markers of Disease Progression MND Research Research we fund

Defining disease progression in MND from MRI ‘snapshots’

26 June 201629 April 2022

Reading Time: 2 minutesAlthough conventional brain magnetic resonance imaging (MRI) scans are often normal in people with MND, more sophisticated MRI techniques have shown changes in the structure

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Markers of Disease Progression MND Research Research we fund

Using a new imaging technique to shed light on changes to nerve cells in MND

25 June 201629 April 2022

Reading Time: 2 minutesMagnetic Resonance Imaging (MRI) technology is advancing rapidly as a tool for diagnosing and monitoring disease. In MND, MRI scans are used to understand changes

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