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Author: Sara Bolton

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Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

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Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

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Causes and disease mechanisms MND Research Research we fund

Using iPSCs to understand why motor neurones lose their normal function in MND

28 June 20168 April 2022

Reading Time: 2 minutesResearchers can create human motor neurones exhibiting signs of MND in the lab by taking skin cells from a person living with MND and reprogramming

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Causes and disease mechanisms MND Research Research we fund

Transforming skin cells into nerve cells to understand MND gene mutations

27 June 201629 April 2022

Reading Time: 2 minutesIn previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human

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Markers of Disease Progression MND Research Research we fund

Defining disease progression in MND from MRI ‘snapshots’

26 June 201629 April 2022

Reading Time: 2 minutesAlthough conventional brain magnetic resonance imaging (MRI) scans are often normal in people with MND, more sophisticated MRI techniques have shown changes in the structure

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Markers of Disease Progression MND Research Research we fund

Using a new imaging technique to shed light on changes to nerve cells in MND

25 June 201629 April 2022

Reading Time: 2 minutesMagnetic Resonance Imaging (MRI) technology is advancing rapidly as a tool for diagnosing and monitoring disease. In MND, MRI scans are used to understand changes

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MND Research News

Working together towards a world free from MND

21 June 201629 April 2022

Reading Time: 4 minutesDuring MND Awareness Month we are highlighting some of the research the MND Association funds in our ‘Project a Day’ series. Today, on global ALS/MND

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Markers of Disease Progression MND Research Research we fund

Developing the Biomarkers in Oxford Project

20 June 201629 April 2022

Reading Time: 2 minutesBiomarkers in Oxford (BioMOx) is a research project with the aim of identifying a diagnostic biomarker for MND, which could be used to track the

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MND Research Models of MND Research we fund

Developing a drug screen using nerve cells from a mouse model of MND

18 June 201629 April 2022

Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse

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MND Research Models of MND Research we fund

Can zebrafish help us to learn more about MND?

16 June 201629 April 2022

Reading Time: 2 minutesA team at the Sheffield Institute for Translational Neuroscience are creating a zebrafish model to study the C9orf72 gene mutation in MND, and work out

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