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Category: Causes and disease mechanisms

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Causes and disease mechanisms MND Research Symposium

What causes MND – an update from Dublin

8 December 201629 April 2022

Reading Time: 3 minutesWhat causes MND is the question that so many of us want to know. For the majority of people with MND we know that it

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Causes and disease mechanisms MND Research

Could a Diabetes drug be useful in treating MND?

2 August 2016

Reading Time: 2 minutesToday we announce a new collaboration for a preclinical research study on the diabetes drug liraglutide, in the hope that positive results will lead to

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Causes and disease mechanisms MND Research News Research we fund

New genetic discoveries tell us more about what causes MND – Part 2

27 July 2016

Reading Time: 2 minutesTwo sets of MND genetic results were published yesterday. One of these results was about the importance of a new gene called NEK1. The second

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Causes and disease mechanisms MND Research Research we fund

New genetic discoveries tell us more about what causes MND – Part 1

26 July 2016

Reading Time: 3 minutesToday some exciting news about the genetics of MND was published in the scientific journal Nature Genetics. The results come in two research papers published

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Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

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Causes and disease mechanisms MND Research Research we fund

Motor neurone signalling and the effects of RNA in MND

30 June 201629 April 2022

Reading Time: 2 minutesDr Pietro Fratta completed his first MRC-MND Association Clinical Research Training Fellowship in 2014. Last year he was awarded a new £1.16 million Clinician Scientist

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Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

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Causes and disease mechanisms MND Research Research we fund

Using iPSCs to understand why motor neurones lose their normal function in MND

28 June 20168 April 2022

Reading Time: 2 minutesResearchers can create human motor neurones exhibiting signs of MND in the lab by taking skin cells from a person living with MND and reprogramming

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Causes and disease mechanisms MND Research Research we fund

Transforming skin cells into nerve cells to understand MND gene mutations

27 June 201629 April 2022

Reading Time: 2 minutesIn previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human

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Causes and disease mechanisms MND Research Research we fund

Understanding more about how the cell’s batteries are affected in MND

5 June 201629 April 2022

Reading Time: < 1 minutePhD student Emma Smith has recently started the second year of her MND Association-funded research project at the Sheffield Institute for Translational Neuroscience (SiTRAN) in

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