The Combined Assessments for Function and Survival – CAFS ranks patients’ clinical outcomes based on survival time and change in the ALSFRS-R score. The worst outcome is assigned to the individual who dies first, and the best outcome is assigned to the one who survives with the least functional decline. The scores are then ranked and the mean rank score for each treatment group is calculated. A higher mean CAFS score indicates a better group outcome.

The MND Association’s vision is a world free from MND. Realising this vision means investing more in research, further developing partnerships with the research community, funding bodies and industry, while ensuring that advances in understanding and treating MND are communicated as quickly and effectively as possible. Our Research Development team, composed of 11 members, work hard to achieve this. Principally, the Research Information team within this are involved in communication activities including this MND Research blog.