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Search Results for: TDP-43

A picture of lots of different coloured cartoon neurons
34th Symposium: Basel Causes and disease mechanisms MND Research News Symposium

A new way to detect faulty TDP-43 in MND

11 April 202411 April 2024

Reading Time: 7 minutesResearchers from the University of Aberdeen and the University of Edinburgh have developed a new tool that could help to detect signs of MND in

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A photo of the venue for the conference.
Causes and disease mechanisms Events Genetic Research MND Research Research we fund

Terrific TDP-43 Talks in Trieste

10 October 202311 October 2023

Reading Time: 5 minutesHi there! I’m Dezerae, and I am currently a Lady Edith Wolfson Junior Non-Clinical Research Fellow at the University of Cambridge. My work, supported by

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Causes and disease mechanisms MND Research

Exploring the interaction between TDP-43 and RNA

5 April 20175 May 2022

Reading Time: 3 minutesIn light of the upcoming Biomedical Research Advisory Panel meeting happening on Friday 7 April that will discuss which new research projects the MND Association will fund,

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MND Research Models of MND Research we fund

Investigating C9orf72 and TDP-43 proteins in a fruitfly model of MND

17 June 201629 April 2022

Reading Time: 2 minutesBackground to C9orf72 toxicity We know that damage to C9orf72 (both the gene and the protein it makes) is a crucial step in why some

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MND Research Research we fund Treatments

Flying towards an understanding of TDP-43

13 June 201629 April 2022

Reading Time: 2 minutesIf you looked at the motor neurones of people with MND down the microscope you would see clumps of a protein called TDP-43. Researchers around

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MND Research Research we fund Treatments

Preventing TDP-43 deposits in motor neurones

11 June 201629 April 2022

Reading Time: 2 minutesDeposits of the protein TDP-43 are found within the motor neurones in the majority of cases of MND, and are considered a pathological hallmark of

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Causes and disease mechanisms MND Research Research we fund

The role of the protein TDP-43 in MND due to C9orf72 mutations

3 June 201629 April 2022

Reading Time: 2 minutesMistakes in the C9orf72 gene are the most common cause of inherited MND, and can be linked to about 40% of all cases. Now that

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MND Research News Research we fund

An insight into TDP-43 – An ENCALS 2015 meeting report

19 June 201520 April 2022

Reading Time: 3 minutesMedical Research Council (MRC)/ MND Association Lady Edith Wolfson Clinical Fellow, Dr Jakub Scaber, attended the European Network for a Cure of ALS (ENCALS) meeting

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MND Research News Research we fund

TDP-43: A protein that lingers on..

4 March 201419 April 2022

Reading Time: 2 minutesMND Association-funded researchers from the University of Liverpool have published results in the prestigious open access journal Proceedings of the National Academy of Science. Under the

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MND Research News

The 11th Annual ENCALS meeting highlights how TDP-43 spreads in MND

6 June 201314 April 2022

Reading Time: 4 minutesThe European Network for a cure of ALS (ENCALS) held its 11th Annual meeting in Sheffield from 31 May to the 2 June. The weekend

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