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Category: Causes and disease mechanisms

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Causes and disease mechanisms MND Research Research we fund

Finding a connection between the cell’s waste disposal system and MND

4 June 201629 April 2022

Reading Time: 2 minutesJust like when we put out our recycling every week, the cells in our body have their own recycling system too. One of the recycling

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Causes and disease mechanisms MND Research Research we fund

The role of the protein TDP-43 in MND due to C9orf72 mutations

3 June 201629 April 2022

Reading Time: 2 minutesMistakes in the C9orf72 gene are the most common cause of inherited MND, and can be linked to about 40% of all cases. Now that

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Causes and disease mechanisms MND Research Research we fund

Understanding and preventing the protein build-up that can cause nerve cells to die

2 June 201629 April 2022

Reading Time: 2 minutesPrior research has already shown that build-up of the protein TDP-43 is found in the majority of cases of MND (irrespective of whether it was

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Causes and disease mechanisms MND Research Research we fund

Using fruit flies to understand a genetic cause of MND

1 June 201629 April 2022

Reading Time: 2 minutesMistakes in a gene known as ALS5, or spatacsin, cause a rare form of inherited MND that develops at a much earlier age than most

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Causes and disease mechanisms MND Research News

Pesticides linked to increased risk of developing MND

10 May 201628 April 2022

Reading Time: 3 minutesThe results from a study looking at the possible links between exposure to environmental toxins (found in pesticides) and motor neurone disease (MND) was published

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Causes and disease mechanisms MND Research News

More clues to the inner workings of the C9orf72 gene

4 April 2016

Reading Time: 2 minutesContinuing the ‘gene hunting theme’ on from our last blog post on Project MinE, a recently published study has shed more light on the C9orf72

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Causes and disease mechanisms MND Research News Research we fund

Looking for MND genes: Project MinE update

17 March 201616 February 2021

Reading Time: 3 minutesProject MinE is an international genetics project that is analysing DNA from people with MND in detail. For the majority of people with MND, the disease

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Causes and disease mechanisms MND Research Symposium

New ALS gene represents another small step

13 December 201528 April 2022

Reading Time: 2 minutesIt wouldn’t be the Symposium without a new gene discovery. Although technology has allowed incredible advances in the gene-hunting field, this is countered by the

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Causes and disease mechanisms MND Research Symposium

Spreading the seeds of an idea: MND disease pathology

13 December 201528 April 2022

Reading Time: 3 minutesWith motor neurone disease (MND), the muscle weakness almost always starts in a single part of the body, with the weakness then spreading to other

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Causes and disease mechanisms MND Research Symposium

The BMAA story in a nutshell

12 December 201528 April 2022

Reading Time: 3 minutesResearch into the neurodegenerative condition known as Guam ALS-Parkinson Dementia Complex (ALS-PDC) has tended to find itself slightly isolated from the mainstream MND/ALS research world

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