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Category: Causes and disease mechanisms

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Causes and disease mechanisms MND Research Research we fund

Understanding and preventing the protein build-up that can cause nerve cells to die

2 June 201629 April 2022

Reading Time: 2 minutesPrior research has already shown that build-up of the protein TDP-43 is found in the majority of cases of MND (irrespective of whether it was

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Causes and disease mechanisms MND Research Research we fund

Using fruit flies to understand a genetic cause of MND

1 June 201629 April 2022

Reading Time: 2 minutesMistakes in a gene known as ALS5, or spatacsin, cause a rare form of inherited MND that develops at a much earlier age than most

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Causes and disease mechanisms MND Research News

Pesticides linked to increased risk of developing MND

10 May 201628 April 2022

Reading Time: 3 minutesThe results from a study looking at the possible links between exposure to environmental toxins (found in pesticides) and motor neurone disease (MND) was published

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Causes and disease mechanisms MND Research News

More clues to the inner workings of the C9orf72 gene

4 April 2016

Reading Time: 2 minutesContinuing the ‘gene hunting theme’ on from our last blog post on Project MinE, a recently published study has shed more light on the C9orf72

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Causes and disease mechanisms MND Research News Research we fund

Looking for MND genes: Project MinE update

17 March 201616 February 2021

Reading Time: 3 minutesProject MinE is an international genetics project that is analysing DNA from people with MND in detail. For the majority of people with MND, the disease

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26th Symposium: Orlando 2015 Causes and disease mechanisms MND Research Symposium

New ALS gene represents another small step

13 December 201528 April 2022

Reading Time: 2 minutesIt wouldn’t be the Symposium without a new gene discovery. Although technology has allowed incredible advances in the gene-hunting field, this is countered by the

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26th Symposium: Orlando 2015 Causes and disease mechanisms MND Research Symposium

Spreading the seeds of an idea: MND disease pathology

13 December 201528 April 2022

Reading Time: 3 minutesWith motor neurone disease (MND), the muscle weakness almost always starts in a single part of the body, with the weakness then spreading to other

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26th Symposium: Orlando 2015 Causes and disease mechanisms MND Research Symposium

The BMAA story in a nutshell

12 December 201528 April 2022

Reading Time: 3 minutesResearch into the neurodegenerative condition known as Guam ALS-Parkinson Dementia Complex (ALS-PDC) has tended to find itself slightly isolated from the mainstream MND/ALS research world

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Causes and disease mechanisms MND Research Research we fund

Hunting for clues about the genetic causes of FTD and MND

9 October 20152 August 2024

Reading Time: 3 minutesYesterday we published an introductory blog on frontotemporal dementia (FTD) and described how it is sometimes found in combination with MND. Today we are looking

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Causes and disease mechanisms MND Research

Do retroviruses contribute to the common, sporadic form of MND?

1 October 2015

Reading Time: 2 minutesNew research from scientists at the American National Institute of Neurological Disorders and Stroke in Bethesda suggest that they might. In a research paper published

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