Skip to content
  • Facebook
  • X
  • Instagram
  • Email

MND Research Blog

Taking you behind the scenes of MND research

  • Home
  • About this blog
    • About us
    • How to use this blog
      • Comments policy
  • Blog Categories
    • Research we fund
    • Treatments
      • Clinical Trials
      • Unproven treatments
    • Causes and disease mechanisms
    • Markers of Disease Progression
    • Models of MND
    • Healthcare
    • Symposium
      • 36th Symposium: San Diego
      • 35th Symposium: Montreal
      • 34th Symposium: Basel
  • Back to Basics
  • Life in the Lab
  • Glossary

Category: Causes and disease mechanisms

  • Home
  • Causes and disease mechanisms
  • Page 14
Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

Read More
Causes and disease mechanisms MND Research Research we fund

Motor neurone signalling and the effects of RNA in MND

30 June 201629 April 2022

Reading Time: 2 minutesDr Pietro Fratta completed his first MRC-MND Association Clinical Research Training Fellowship in 2014. Last year he was awarded a new £1.16 million Clinician Scientist

Read More
Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

Read More
Causes and disease mechanisms MND Research Research we fund

Using iPSCs to understand why motor neurones lose their normal function in MND

28 June 20168 April 2022

Reading Time: 2 minutesResearchers can create human motor neurones exhibiting signs of MND in the lab by taking skin cells from a person living with MND and reprogramming

Read More
Causes and disease mechanisms MND Research Research we fund

Transforming skin cells into nerve cells to understand MND gene mutations

27 June 201629 April 2022

Reading Time: 2 minutesIn previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human

Read More
Causes and disease mechanisms MND Research Research we fund

Understanding more about how the cell’s batteries are affected in MND

5 June 201629 April 2022

Reading Time: < 1 minutePhD student Emma Smith has recently started the second year of her MND Association-funded research project at the Sheffield Institute for Translational Neuroscience (SiTRAN) in

Read More
Causes and disease mechanisms MND Research Research we fund

Finding a connection between the cell’s waste disposal system and MND

4 June 201629 April 2022

Reading Time: 2 minutesJust like when we put out our recycling every week, the cells in our body have their own recycling system too. One of the recycling

Read More
Causes and disease mechanisms MND Research Research we fund

The role of the protein TDP-43 in MND due to C9orf72 mutations

3 June 201629 April 2022

Reading Time: 2 minutesMistakes in the C9orf72 gene are the most common cause of inherited MND, and can be linked to about 40% of all cases. Now that

Read More
Causes and disease mechanisms MND Research Research we fund

Understanding and preventing the protein build-up that can cause nerve cells to die

2 June 201629 April 2022

Reading Time: 2 minutesPrior research has already shown that build-up of the protein TDP-43 is found in the majority of cases of MND (irrespective of whether it was

Read More
Causes and disease mechanisms MND Research Research we fund

Using fruit flies to understand a genetic cause of MND

1 June 201629 April 2022

Reading Time: 2 minutesMistakes in a gene known as ALS5, or spatacsin, cause a rare form of inherited MND that develops at a much earlier age than most

Read More

Posts pagination

Previous 1 … 13 14 15 … 23 Next

Useful Links

  • MND Association Website
  • International Symposium
  • MND Clinical Studies Group

The official blog of the

Copyright © 2025 MND Research Blog - MND Association. All rights reserved. Registered Charity no. 294354