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A ‘wee molecule’: the tiny urinary biomarker neopterin and its role in MND progression

A ‘wee molecule’: the tiny urinary biomarker neopterin and its role in MND progression

Reading Time: 6 minutes My name is Stephanie Shepheard, and I am a Research Associate in the Motor Neuron Disease & Neurotrophic Research Laboratory (MND&NR Lab), Flinders Health & Medicine Research Institute in the College of Medicine & Public Health at Flinders University, South Australia. I measure biological changes, or biomarkers, that may tell us something useful about motor…

Symposium Spotlight: Biomarkers in MND – improving drug development and clinical trial design

Symposium Spotlight: Biomarkers in MND – improving drug development and clinical trial design

Reading Time: 4 minutes Diagnosing disease faster, accurately predicting disease progression, assessing the ability of a new drug to reach its target – I think we’d all agree that these three things are essential requirements for treating all diseases. But how can we achieve this? The answer may lie in biomarkers. In his plenary talk at last year’s International…

Kennedy’s Disease vs ALS: How muscle patterns can aid diagnosis and perform as a novel biomarker

Reading Time: 3 minutes Researchers from University College London led by Dr Pietro Fratta and Dr John Thornton found that muscle imaging can help distinguish Amyotrophic Lateral Sclerosis (ALS) from Kennedy’s Disease based on the way specific muscle groups deteriorate in each condition. The method can also help assess the severity of the disease. ALS is a rapidly progressing…