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Text reads: Celebrating 10 years of our non-clinical fellowship programme

Celebrating 10 years of our Non-Clinical Fellowships!

18 August 202518 August 2025 Eleanor Green

Making Gene Therapies Smarter and Safer

28 July 202528 July 2025 Gen Temple

MND EnCouRage UK 2025: Encouraging the future leaders of MND research

22 July 202523 July 2025 Eleanor Green

MND EnCouRage UK: Looking back at four years of supporting the next generation of MND researchers

14 July 202514 July 2025 Katy Barnes

How can biomarkers be used in clinical trials in MND?

8 July 20258 July 2025 Research Information Team

What are clinical trials?

8 July 20258 July 2025 Research Information Team
Markers of Disease Progression MND Research Research we fund

Investigating miRNAs as a biomarker for MND

22 June 201629 April 2022

Reading Time: 2 minutesThere is a critical need to find a biomarker for MND to speed up diagnosis, monitor disease progression and improve clinical trials. A biomarker is

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MND Research News

Working together towards a world free from MND

21 June 201629 April 2022

Reading Time: 4 minutesDuring MND Awareness Month we are highlighting some of the research the MND Association funds in our ‘Project a Day’ series. Today, on global ALS/MND

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Markers of Disease Progression MND Research Research we fund

Developing a blood test for MND by linking changes in the brain and spinal cord

21 June 201629 April 2022

Reading Time: 3 minutesDeveloping a way to rapidly diagnose and track how MND progresses over time is a ‘holy grail’ of MND research. The search for so called

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Markers of Disease Progression MND Research Research we fund

Developing the Biomarkers in Oxford Project

20 June 201629 April 2022

Reading Time: 2 minutesBiomarkers in Oxford (BioMOx) is a research project with the aim of identifying a diagnostic biomarker for MND, which could be used to track the

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MND Research Models of MND Research we fund

Using DNA Bank samples to create iPSC models of MND

19 June 201629 April 2022

Reading Time: 2 minutesInduced pluripotent stem cell (iPSC) technology has enabled researchers to create and study living human motor neurones in the lab, derived originally from patient skin

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MND Research Models of MND Research we fund

Developing a drug screen using nerve cells from a mouse model of MND

18 June 201629 April 2022

Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse

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MND Research Models of MND Research we fund

Investigating C9orf72 and TDP-43 proteins in a fruitfly model of MND

17 June 201629 April 2022

Reading Time: 2 minutesBackground to C9orf72 toxicity We know that damage to C9orf72 (both the gene and the protein it makes) is a crucial step in why some

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MND Research Models of MND Research we fund

Can zebrafish help us to learn more about MND?

16 June 201629 April 2022

Reading Time: 2 minutesA team at the Sheffield Institute for Translational Neuroscience are creating a zebrafish model to study the C9orf72 gene mutation in MND, and work out

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MND Research Research we fund Treatments

Correcting the early damage seen in MND

15 June 201629 April 2022

Reading Time: 2 minutesPrevious research in humans and zebrafish has shown that before symptoms arise in MND, early changes occur in the interneurones. This type of nerve cell

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MND Research Research we fund Treatments

Protecting motor neurones against oxidative stress in MND

14 June 201629 April 2022

Reading Time: 2 minutesDuring the early stages of MND it is proposed that motor neurones are more susceptible to an imbalance of oxygen within the cells, known as

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