Mice and Marbles: A CRISPR Model of Motor Neurone Disease
Reading Time: 6 minutes A new model of MND in mice made using CRISPR technology to edit TDP-43. The mice have cognitive changes and have uncovered new insights into MND- FTD mechanisms.
Tag: Jemeen Sreedharan
Flying towards an understanding of TDP-43
Reading Time: 2 minutes If you looked at the motor neurones of people with MND down the microscope you would see clumps of a protein called TDP-43. Researchers around the world are working to find why these clumps form and how they are linked to MND. Dr Jemeen Sreedharan has been looking at the effects of TDP-43 in fruit…
MND Association fellowships awarded to promising clinicians | 2013 | MND Association
Reading Time: < 1 minute Two MND clinicians have been awarded Medical Research Council (MRC) /MND Association Lady Edith Wolfson Clinical Research Fellowships to help advance our understanding of MND while moulding future experts. The MND Association Lady Edith Wolfson Clinical Research Fellowship scheme plays a vital role in helping us strengthen and translate emerging knowledge from the lab to…