Reading Time: 4 minutesIn April 2016, Dr Jackie Mitchell gave a talk at the Regional Conference in Gatwick to explain the aims of her three year MND Association
Tag: TDP-43
Reading Time: 3 minutesIn light of the upcoming Biomedical Research Advisory Panel meeting happening on Friday 7 April that will discuss which new research projects the MND Association will fund,
Reading Time: 3 minutesThe MND Association are funding Prof Kevin Talbot, Dr Ruxandra Dafinca (née Mutihac) and colleagues at the University of Oxford, who are investigating the link
Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse
Reading Time: 2 minutesBackground to C9orf72 toxicity We know that damage to C9orf72 (both the gene and the protein it makes) is a crucial step in why some
Reading Time: 2 minutesIf you looked at the motor neurones of people with MND down the microscope you would see clumps of a protein called TDP-43. Researchers around
Reading Time: 2 minutesDeposits of the protein TDP-43 are found within the motor neurones in the majority of cases of MND, and are considered a pathological hallmark of
Reading Time: 2 minutesMistakes in the C9orf72 gene are the most common cause of inherited MND, and can be linked to about 40% of all cases. Now that
Reading Time: 2 minutesPrior research has already shown that build-up of the protein TDP-43 is found in the majority of cases of MND (irrespective of whether it was