Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse
Tag: TDP-43
Reading Time: 2 minutesIf you looked at the motor neurones of people with MND down the microscope you would see clumps of a protein called TDP-43. Researchers around
Reading Time: 2 minutesDeposits of the protein TDP-43 are found within the motor neurones in the majority of cases of MND, and are considered a pathological hallmark of
Reading Time: 2 minutesMistakes in the C9orf72 gene are the most common cause of inherited MND, and can be linked to about 40% of all cases. Now that
Reading Time: 2 minutesPrior research has already shown that build-up of the protein TDP-43 is found in the majority of cases of MND (irrespective of whether it was
Reading Time: 3 minutesWith motor neurone disease (MND), the muscle weakness almost always starts in a single part of the body, with the weakness then spreading to other
Reading Time: 3 minutesYesterday we published an introductory blog on frontotemporal dementia (FTD) and described how it is sometimes found in combination with MND. Today we are looking
Reading Time: 2 minutesNew research from scientists at the American National Institute of Neurological Disorders and Stroke in Bethesda suggest that they might. In a research paper published
Reading Time: < 1 minuteResearch published yesterday on 3 June 2014 in the prestigious journal Nature Communications, highlights key insights into how the protein TDP-43 may cause motor neurones to