Close
Studentship success – next steps for Matthew Nolan

Studentship success – next steps for Matthew Nolan

Reading Time: 5 minutes Guest researcher blog post written by Matthew Nolan. My name is Matthew, I’m currently a post-doctoral researcher at Massachusetts General Hospital and Harvard Medical School in the USA, supported by a Cullen Education and Research Young Investigator Award. Last year I finished my MND Association-funded PhD at the University of Oxford, where I was supervised by…

‘Hero’ proteins assemble to stop toxic clumps

‘Hero’ proteins assemble to stop toxic clumps

Reading Time: 5 minutes Much like fictional superheroes who are dedicated to protecting the vulnerable with their supernatural abilities, a newly discovered class of ‘Hero’ proteins with unusual properties can prevent toxic protein aggregation seen in several neurodegenerative disorders, such as MND. This finding may have potential for new treatments and applications in biotechnology.

The ALS RAP

The ALS RAP

Reading Time: 5 minutes Yesterday, we were delighted to unveil a new research collaboration that we believe will greatly improve the quality and pace of MND research – not only in understanding the cellular processes that cause motor neurons to degenerate, but also in helping with drug discovery and development. The Amyotrophic Lateral Sclerosis Reproducible Antibody Platform (ALS RAP) isn’t…

Exploring the interaction between TDP-43 and RNA

Reading Time: 3 minutes In light of the upcoming Biomedical Research Advisory Panel meeting happening on Friday 7 April that will discuss which new research projects the MND Association will fund, we are pleased to report on the progress of one of our already-funded researchers. In their three year project, funded by the MND Association, Prof Annalisa Pastore (King’s College London)…

Transforming skin cells into nerve cells to understand MND gene mutations

Reading Time: 2 minutes In previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human motor neurones to die. These studies were carried out using an impressive piece of lab technology, called induced pluripotent stem cell (iPSC) technology. iPSC technology allows skin cells to be…