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Tag: TDP-43

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Causes and disease mechanisms MND Research Symposium

Spreading the seeds of an idea: MND disease pathology

13 December 201528 April 2022

Reading Time: 3 minutesWith motor neurone disease (MND), the muscle weakness almost always starts in a single part of the body, with the weakness then spreading to other

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Causes and disease mechanisms MND Research Research we fund

Hunting for clues about the genetic causes of FTD and MND

9 October 20152 August 2024

Reading Time: 3 minutesYesterday we published an introductory blog on frontotemporal dementia (FTD) and described how it is sometimes found in combination with MND. Today we are looking

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Causes and disease mechanisms MND Research

Do retroviruses contribute to the common, sporadic form of MND?

1 October 2015

Reading Time: 2 minutesNew research from scientists at the American National Institute of Neurological Disorders and Stroke in Bethesda suggest that they might. In a research paper published

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MND Research News Research we fund

Another piece in the MND Jigsaw..

4 June 201419 April 2022

Reading Time: < 1 minuteResearch published yesterday on 3 June 2014 in the prestigious journal Nature Communications, highlights key insights into how the protein TDP-43 may cause motor neurones to

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MND Research News Research we fund

TDP-43: A protein that lingers on..

4 March 201419 April 2022

Reading Time: 2 minutesMND Association-funded researchers from the University of Liverpool have published results in the prestigious open access journal Proceedings of the National Academy of Science. Under the

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MND Research Models of MND Research we fund Symposium

Unravelling TDP43 toxicity

7 December 201314 April 2022

Reading Time: 4 minutesBackground to TDP43 A characteristic sign of motor neurones affected by motor neurone disease is the clumps of protein visible down a microscope. Although these

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MND Research News

The 11th Annual ENCALS meeting highlights how TDP-43 spreads in MND

6 June 201314 April 2022

Reading Time: 4 minutesThe European Network for a cure of ALS (ENCALS) held its 11th Annual meeting in Sheffield from 31 May to the 2 June. The weekend

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MND Research Models of MND News Research we fund

MND stem cell study identifies TDP-43 astrocytes as not toxic to motor neurones

12 February 201314 April 2022

Reading Time: 3 minutesFunded by the MND Association, international researchers have used stem cell technology to learn more about the relationship between motor neurones and their support cells.

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MND Research

MND Association fellowships awarded to promising clinicians | 2013 | MND Association

28 January 2013

Reading Time: < 1 minuteTwo MND clinicians have been awarded Medical Research Council (MRC) /MND Association Lady Edith Wolfson Clinical Research Fellowships to help advance our understanding of MND

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MND Research

MND Research in 2012

21 January 201314 April 2022

Reading Time: 4 minutesAt this time of year, it’s always good to look back on the previous year to see just how far we’ve really come. We’re pleased

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