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Of yeast and men: reducing toxic effects of TDP-43 as a potential treatment for MND

Reading Time: 4 minutes A collaborative American research group, led by Prof Aaron Gitler from Stanford University School of Medicine in California, has identified a potential therapeutic target for MND using yeast. The toxic activity of the MND-linked protein TDP-43 was suppressed when a gene called DBR1 was deleted from yeast and mammal cells. The study marks the first…