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Category: Models of MND

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MND Research Models of MND Research we fund

Developing a drug screen using nerve cells from a mouse model of MND

18 June 201629 April 2022

Reading Time: 2 minutesIn a previous research project funded by the MND Association, Prof Kevin Talbot and colleagues from the University of Oxford developed a new TDP-43 mouse

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MND Research Models of MND Research we fund

Investigating C9orf72 and TDP-43 proteins in a fruitfly model of MND

17 June 201629 April 2022

Reading Time: 2 minutesBackground to C9orf72 toxicity We know that damage to C9orf72 (both the gene and the protein it makes) is a crucial step in why some

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MND Research Models of MND Research we fund

Can zebrafish help us to learn more about MND?

16 June 201629 April 2022

Reading Time: 2 minutesA team at the Sheffield Institute for Translational Neuroscience are creating a zebrafish model to study the C9orf72 gene mutation in MND, and work out

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Causes and disease mechanisms MND Research Models of MND Research we fund

Pretty ‘fly’ for a fruit fly

27 January 20152 August 2024

Reading Time: 4 minutes  Dr Frank Hirth is one of the world’s leading fruit fly MND researchers. Based at the Institute of Psychiatry, Psychology and Neuroscience at King’s College

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MND Research Models of MND News Research we fund

Measuring the nerve impulse

12 January 201520 April 2022

Reading Time: 4 minutesResearchers identify that loss of nerve signalling may be an early sign of MND Published in Nature Communications on 12 January 2015, Association-funded PhD student Anna-Claire

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25th Symposium: Brussels 2014 MND Research Models of MND Research we fund Symposium

Science in neon flashing lights

6 December 201419 April 2022

Reading Time: 3 minutesThe opening presentation of this morning’s session of the International Symposium on ALS/MND set the tone for the rest of the day – almost literally,

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25th Symposium: Brussels 2014 Markers of Disease Progression MND Research Models of MND Research we fund Symposium

A taste of Brussels…

21 November 201419 April 2022

Reading Time: 3 minutesOn 4 November, we welcomed two of our funded researchers to our offices in Northampton. Ruxandra Mutihac and Matt Gabel gave us a ‘taste’ of what’s to come for

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Causes and disease mechanisms MND Research Models of MND Research we fund

Our DNA Bank: the times they are a changing…

28 October 201419 April 2022

Reading Time: 3 minutesThis autumn sees an exciting new development in the MND Association’s DNA Bank. Researchers can now use the samples within it to understand why motor

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Causes and disease mechanisms Markers of Disease Progression MND Research Models of MND Research we fund Treatments

Very ‘ice’ research

22 August 201419 April 2022

Reading Time: 3 minutesThe ALS #icebucketchallenge, which started in America, has now well and truly hit the UK! The social media craze has seen thousands of people getting

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Causes and disease mechanisms MND Research Models of MND News Research we fund

Toxic proteins may cause motor neurones to die in C9orf72 MND

7 August 201419 April 2022

Reading Time: 4 minutesMND Association and Alzheimer’s Research UK-funded researchers from University College London have identified that toxic proteins may cause motor neurones to die in C9orf72 MND

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