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Tag: FTD

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Causes and disease mechanisms MND Research Models of MND

Mice and Marbles: A CRISPR Model of Motor Neurone Disease

23 March 20182 August 2024

Reading Time: 6 minutesA new model of MND in mice made using CRISPR technology to edit TDP-43. The mice have cognitive changes and have uncovered new insights into MND- FTD mechanisms.

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Causes and disease mechanisms MND Research

Exploring the interaction between TDP-43 and RNA

5 April 20175 May 2022

Reading Time: 3 minutesIn light of the upcoming Biomedical Research Advisory Panel meeting happening on Friday 7 April that will discuss which new research projects the MND Association will fund,

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Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

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Healthcare MND Research Research we fund

Research on the best practical support for people with cognitive change

7 June 2016

Reading Time: 2 minutesWe know that some people with MND will be affected by cognitive change and a small proportion of these will develop frontotemporal dementia (FTD). The

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Healthcare MND Research Research we fund

Is frontotemporal dementia different when found with MND?

6 June 201629 April 2022

Reading Time: 2 minutesSome people with MND develop an increasingly recognised form of dementia, known as frontotemporal dementia  or FTD (for more information visit http://www.ftdtalk.org/). The main symptoms

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Causes and disease mechanisms MND Research News

More clues to the inner workings of the C9orf72 gene

4 April 2016

Reading Time: 2 minutesContinuing the ‘gene hunting theme’ on from our last blog post on Project MinE, a recently published study has shed more light on the C9orf72

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26th Symposium: Orlando 2015 Causes and disease mechanisms MND Research Symposium

Spreading the seeds of an idea: MND disease pathology

13 December 201528 April 2022

Reading Time: 3 minutesWith motor neurone disease (MND), the muscle weakness almost always starts in a single part of the body, with the weakness then spreading to other

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Healthcare Research we fund

Are there differences between FTD alone and FTD-MND?

10 October 201528 April 2022

Reading Time: 3 minutesThe last of our FTD awareness week blog posts is focussing on a healthcare project looking into FTD (frontotemporal dementia) and FTD-MND (FTD when combined with

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Causes and disease mechanisms MND Research Research we fund

Hunting for clues about the genetic causes of FTD and MND

9 October 20152 August 2024

Reading Time: 3 minutesYesterday we published an introductory blog on frontotemporal dementia (FTD) and described how it is sometimes found in combination with MND. Today we are looking

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Research we fund

Cognitive Change and MND

8 October 201528 April 2022

Reading Time: 3 minutesIn addition to the muscle weakness and wasting, MND also presents with non-motor symptoms, one of the most common being cognitive change. Research has already

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