Reading Time: 6 minutes Recent research, led by Professor Guillaume Hautbergue at the University of Sheffield, has found a potential new method of preventing nerve cell death in the most common genetic form of MND. This new method could, with further studies, lead to the development of a potential therapy for C9orf72 MND, and a type of dementia called…
Reading Time: 5 minutes This is blog number 8 in our ‘Symposium Blogathon’ – counting down to the 32nd International Symposium on ALS/MND. Numbers in bold green type correspond to the code in the abstract book. Click on the number to be redirected to the full abstract (the page might take a minute to load). Up to half of…
Reading Time: 4 minutes Due to the collaboration, hard work and partnerships with people affected by motor neurone disease (MND) who generously take part in research, new pieces of the complex MND puzzle continue to be found. These pieces can come in many forms and one such type of discovery is of the genes that cause MND – in…
Reading Time: 3 minutes Written by Rachel Boothman and Kaye Stevens This blog is part of the ‘Highlights from Glasgow’ collection of articles, where you can read about the content of some of the talks and posters presented at the 29th International Symposium on ALS/MND. Exploration into cognition and frontotemporal dementia with MND/ALS continues to attract attention. At the…
Reading Time: 3 minutes Motor Neurone Disease (MND), as the name suggests, is known as a disease of motor neurons, a specific type of neurons that co-ordinate our voluntary movement, leading to loss of the ability to move, speak and breathe. And perhaps because the main focus often falls on the rapidly-progressing physical symptoms and their management, the way…
Reading Time: 5 minutes In recent news, a number of press releases highlighted a paper published in the journal Cell, in which scientists, under the leadership of the University of Toronto’s Professor Peter St George-Hyslop, and in collaboration with University of Cambridge, described the process of how the FUS protein leads to the development of motor neurone disease (MND)…
Reading Time: 6 minutes A new model of MND in mice made using CRISPR technology to edit TDP-43. The mice have cognitive changes and have uncovered new insights into MND- FTD mechanisms.
Reading Time: 3 minutes In light of the upcoming Biomedical Research Advisory Panel meeting happening on Friday 7 April that will discuss which new research projects the MND Association will fund, we are pleased to report on the progress of one of our already-funded researchers. In their three year project, funded by the MND Association, Prof Annalisa Pastore (King’s College London)…
Reading Time: 2 minutes Researchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper on their work has recently been published in the EMBO Journal. A change or mutation to the C9orf72 gene is linked to about 40% of cases of inherited MND. We…
Reading Time: 2 minutes We know that some people with MND will be affected by cognitive change and a small proportion of these will develop frontotemporal dementia (FTD). The symptoms of cognitive change include changes in planning and decision making. To help support people with MND who have these symptoms, and their families and carers, we need to firstly…
