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Tag: genes

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What is DNA and how is it involved in MND?

14 August 202414 August 2024

Reading Time: 4 minutesOur DNA holds the instructions to many important processes within our body. Some people with MND may have changes in their DNA which contribute to

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34th Symposium: Basel Causes and disease mechanisms Clinical Trials Genetic Research Markers of Disease Progression MND Research Symposium Treatments

The power of genetics in MND research

2 February 20242 February 2024

Reading Time: 9 minutesResearch into genetic causes of MND has greatly increased over the last few decades and gene changes have since been found to play a role

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MND Research News Research we fund

New insights into MND: 5 more genetic variants found

21 April 202121 April 2021

Reading Time: 5 minutesA recent study has assessed the extent to which genetics plays a role in the development of MND, in both familial and non-familial (sporadic) forms

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Causes and disease mechanisms MND Research News Research we fund

Should routine genetic testing be considered for all cases of MND?

17 February 202118 February 2021

Reading Time: 9 minutesA paper arising from research carried out at the University of Sheffield as part of the AMBRoSIA biobank, and in collaboration with the international Project

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MND Research Treatments

Lithium revisited: Is there a baby in the bathwater?

13 October 20175 May 2022

Reading Time: 3 minutesAt last year’s Airlie House workshop to develop new ALS/MND Clinical Trial Guidelines the focus was, of course, on MND, but there was also important input

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Causes and disease mechanisms MND Research Research we fund

ANXA11 – another gene closer to understanding ALS

4 May 20175 May 2022

Reading Time: 3 minutesA new research paper has been published today in the Science Translational Medicine journal, describing a new gene implicated in developing MND. What is this gene

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Healthcare MND Research

Families for the Treatment of Hereditary MND (FaTHoM)

20 February 2017

Reading Time: 2 minutesScientists from the University of Oxford have set up ‘Families for the Treatment of Hereditary MND’ (FaTHoM), an initiative to bring together the community of

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Causes and disease mechanisms MND Research News Research we fund

New genetic discoveries tell us more about what causes MND – Part 2

27 July 2016

Reading Time: 2 minutesTwo sets of MND genetic results were published yesterday. One of these results was about the importance of a new gene called NEK1. The second

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Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

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Causes and disease mechanisms MND Research Research we fund

Using fruit flies to understand a genetic cause of MND

1 June 201629 April 2022

Reading Time: 2 minutesMistakes in a gene known as ALS5, or spatacsin, cause a rare form of inherited MND that develops at a much earlier age than most

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