mitochondria Archives

Boosting energy in nerve cells is a promising target for MND treatments

7 January 20215 February 2021Research Information Team14 Comments

Reading Time: 3 minutes A study conducted by researchers at the Euan MacDonald Centre at the University of Edinburgh has shed light on how improving the function of mitochondria – the power supply of nerve cells – could be a potential treatment for motor neurone disease, paper published this week in the journal, Acta Neuropathologica (2021). This study paves…

The FUS with faulty mitochondria – the powerhouse of the cell

3 August 202031 July 2020Research Information Team5 Comments

Reading Time: 3 minutes Guest researcher blog post written by Darija Šoltić. Originally from Croatia, I came to the UK to do my PhD in neuroscience, where I worked on spinal muscular atrophy, a debilitating childhood motor neuron disease (MND). Earlier this year, I joined the Ruepp group (led by Dr Marc-David Ruepp) at the UK Dementia Research Institute…

Focusing on mitochondria – a potential target for early MND treatment?

14 August 20199 July 2020Mandy Spencer3 Comments

Reading Time: 3 minutes Dr Arpan Mehta, one of our Lady Edith Wolfson Clinical Fellows, and his team at the Euan MacDonald Centre at the University of Edinburgh have recently carried out a systematic review and meta-analysis of the pre-clinical literature (studies using animal models) to assess the therapeutic potential of targeting mitochondrial dysfunction in MND, examining if these…

Understanding more about how the cell’s batteries are affected in MND

5 June 201629 April 2022Belinda Cupid1 Comment

Reading Time: < 1 minute PhD student Emma Smith has recently started the second year of her MND Association-funded research project at the Sheffield Institute for Translational Neuroscience (SiTRAN) in Sheffield (our project reference: 870-792). With her supervisors Dr Kurt De Vos and Dr Andrew Grierson she is investigating the role of mitochondria in C9orf72-related MND. Mitochondria are the cell’s…

A healthy control – Dr Scott Allen

7 June 201419 April 2022Research Information Team4 Comments

Reading Time: 2 minutes Dr Scott Allen is a Senior Post Doctoral Researcher at the Sheffield Institute for Translational Neuroscience (SITraN). Here he blogs about his experience as a research volunteer in an MRI scanner. Today, as part of on-going work by Doctor Tom Jenkins and Prof Pamela Shaw at the Sheffield Institute for Translational Neuroscience (SITraN), I volunteered…