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Spinal Muscular Atrophy – final stages of development of a treatment

Reading Time: 2 minutes In the Sheffield Institute for Translational Neuroscience (SITraN), the gene therapy group led by Prof Mimoun Azzouz is approaching the final stages of preclinical development of a treatment for Spinal Muscular Atrophy (a childhood disease of the motor neurones). Here Chris Binny explains more about the group’s work. About Spinal Muscular Atrophy Spinal muscular atrophy…

New MND Association Lectureship in Translational Neuroscience

Reading Time: < 1 minute Dr Richard Mead based at the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield has been awarded the Kenneth Snowman-MND Association Lectureship in Translational Neuroscience. The five-year Kenneth Snowman-MND Association lectureship is aimed to embed preclinical expertise in motor neurone disease (MND) models within SITraN as a national resource. Our Director of…

Jolly Good Fellows!

Reading Time: 6 minutes There’s a scene in the 1969 film Battle of Britain where Laurence Olivier, who plays the Air Chief Marshal, is in a meeting with his two Vice Marshals. One of them complains that they don’t have enough planes; the other is more concerned with keeping the airfields working. Olivier silences them both by telling them that…

Dr Chris McDermott talks about his research at our Annual Conference

Reading Time: 3 minutes This year’s Annual Conference research talk was given by Dr Chris McDermott and focused on his research at the Sheffield Institute for Translational Neuroscience (SiTraN). His talk, adequately named ‘Improving the care and evidence base for symptomatic care’, was a very personal and informative talk to all that attended. Dr McDermott gave a brief introduction…

New fellowship explores how C9ORF72 causes MND

Reading Time: 4 minutes Dr Johnathan Cooper-Knock from the Sheffield Institute for Translational Neuroscience (SITraN) has been awarded with the fifth Medical Research Council (MRC)/MND Association Lady Edith Wolfson Clinical Research Fellowship. Through his three-year fellowship, Dr Cooper-Knock will use the MND Association’s DNA bank to study how recently discovered mistakes (known as mutations) in a gene called C9ORF72