A motor neuron with other cells around it in the background

Reading Time: 5 minutes My current work focuses on looking at the cell types that are affected in MND and how they impact each other. Motor neurons, the main cell type affected in MND, connect our brains and muscles. This connection is what allows us to move. In MND, these cells start to die, which is what leads to progressive paralysis. But motor neurons aren’t the only cell types affected by MND. They are surrounded by many more cells called glia, which have roles in keeping our motor neurons healthy.

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A photo of astrocytes

Reading Time: 5 minutes I’m Hannah, an MND Association-funded first year PhD student at the University of Nottingham. During my undergraduate degree in Biochemistry, also at Nottingham, I had the opportunity to do a project researching MND in the lab, where my interest in MND began. During this project I also met someone who was living with MND, who had come to hear about the research happening in our lab. Hearing his insights into the devastating effects of MND really stuck with me, and I decided I wanted to begin a career in MND research. This led me to my PhD project, in which I am aiming to make a natural type of cell called astrocytes more protective of motor neurones. We hope that this work will inform us of a possible new way to treat MND.

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