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Category: Models of MND

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24th Symposium: Milan 2013 MND Research Models of MND Research we fund Symposium

Unravelling TDP43 toxicity

7 December 201314 April 2022

Reading Time: 4 minutesBackground to TDP43 A characteristic sign of motor neurones affected by motor neurone disease is the clumps of protein visible down a microscope. Although these

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MND Research Models of MND News Research we fund

Same disease.. two very different mice!

14 November 201314 April 2022

Reading Time: 4 minutesThe exact course, duration and rate of progression of MND often varies greatly from person to person; even when there is a known family history

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Clinical Trials MND Research Models of MND News Treatments

Stem cells and growth factors: from bench to bedside

24 June 201314 April 2022

Reading Time: 4 minutesAfter a brilliant first day at ENCALS, which included a talk by Dr Johannes Brettschneider, the second day began with a talk by Thierry Latran

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Causes and disease mechanisms MND Research Models of MND News

The not so powerful omega-3

18 June 201314 April 2022

Reading Time: 4 minutesOmega-3 fatty acids have been in the media a great deal over recent years. They can lower our risk of heart disease and they may

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Causes and disease mechanisms MND Research Models of MND News

The C9orf72 mystery begins to unravel even more of its secrets

5 April 201314 April 2022

Reading Time: 4 minutesIn 2011 an international team of scientists, including three MND Association-funded researchers, identified the elusive C9orf72 gene located on Chromosome 9. Since this ground-breaking discovery,

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MND Research Models of MND News Research we fund

MND stem cell study identifies TDP-43 astrocytes as not toxic to motor neurones

12 February 201314 April 2022

Reading Time: 3 minutesFunded by the MND Association, international researchers have used stem cell technology to learn more about the relationship between motor neurones and their support cells.

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Causes and disease mechanisms MND Research Models of MND News Research we fund

Zebrafish show that ‘connector neurons’ are the key in early stages of MND

30 January 201314 April 2022

Reading Time: 3 minutesA recent study by Motor Neurone Disease Association-funded researcher Dr Tennore Ramesh from the Sheffield Institute for Translational Neuroscience (SITraN) has shown that even before

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23rd Symposium: Chicago 2012 Causes and disease mechanisms MND Research Models of MND News Symposium

Mastering Pac-Man

6 December 201214 April 2022

Reading Time: 3 minutesGrowing up in a seaside town in the 1980s led to me spending a lot of my “formative years” in the local amusement arcades, playing

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Models of MND Treatments

Of yeast and men: reducing toxic effects of TDP-43 as a potential treatment for MND

14 November 2012

Reading Time: 4 minutesA collaborative American research group, led by Prof Aaron Gitler from Stanford University School of Medicine in California, has identified a potential therapeutic target for

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Causes and disease mechanisms MND Research Models of MND News

EPHA4 gene influences survival in MND

30 August 2012

Reading Time: 3 minutesAn international research group spanning seven countries and including 23 researchers has identified a gene that modifies survival in MND. The gene, called EPHA4 was identified through

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