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Global MND awareness day: Hidden challenges of MND research

20 June 202520 June 2025 Eleanor Green

Understanding the ‘hidden middle’ of cognitive change in MND

11 June 202511 June 2025 Mandy Spencer

MIROCALS: breaking down the trial results

9 May 202512 May 2025 Research Information Team

Improving Care at Home: A New Study into Complex Homecare in MND (CHiMND)

1 May 20251 May 2025 Gen Temple

Symposium Highlights: Cells and MND

26 March 202526 March 2025 Katy Barnes

Symposium highlights: A spotlight on glial cells in MND

19 March 202519 March 2025 Libby Moody
Causes and disease mechanisms MND Research News Research we fund

New genetic discoveries tell us more about what causes MND – Part 2

27 July 2016

Reading Time: 2 minutesTwo sets of MND genetic results were published yesterday. One of these results was about the importance of a new gene called NEK1. The second

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Causes and disease mechanisms MND Research Research we fund

New genetic discoveries tell us more about what causes MND – Part 1

26 July 2016

Reading Time: 3 minutesToday some exciting news about the genetics of MND was published in the scientific journal Nature Genetics. The results come in two research papers published

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Causes and disease mechanisms MND Research Research we fund

How faulty proteins disrupt waste recycling and disposal inside nerve cells

1 July 201629 April 2022

Reading Time: 2 minutesResearchers from the Sheffield Institute for Translational Neuroscience (SITraN) at the University of Sheffield have uncovered a new function of the C9orf72 protein. A paper

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Causes and disease mechanisms MND Research Research we fund

Motor neurone signalling and the effects of RNA in MND

30 June 201629 April 2022

Reading Time: 2 minutesDr Pietro Fratta completed his first MRC-MND Association Clinical Research Training Fellowship in 2014. Last year he was awarded a new £1.16 million Clinician Scientist

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Causes and disease mechanisms MND Research Research we fund

Identifying the genetic causes of MND in specific populations

29 June 201629 April 2022

Reading Time: 2 minutesDr Russell McLaughlin from Trinity College Dublin is one of our Junior Non-Clinical Fellows. Our Non-Clinical Fellowships were awarded for the first time last year.

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Causes and disease mechanisms MND Research Research we fund

Using iPSCs to understand why motor neurones lose their normal function in MND

28 June 20168 April 2022

Reading Time: 2 minutesResearchers can create human motor neurones exhibiting signs of MND in the lab by taking skin cells from a person living with MND and reprogramming

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Causes and disease mechanisms MND Research Research we fund

Transforming skin cells into nerve cells to understand MND gene mutations

27 June 201629 April 2022

Reading Time: 2 minutesIn previous research Prof Kevin Talbot and colleagues at the University of Oxford began to understand more about how the C9orf72 gene defect causes human

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Markers of Disease Progression MND Research Research we fund

Defining disease progression in MND from MRI ‘snapshots’

26 June 201629 April 2022

Reading Time: 2 minutesAlthough conventional brain magnetic resonance imaging (MRI) scans are often normal in people with MND, more sophisticated MRI techniques have shown changes in the structure

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Markers of Disease Progression MND Research Research we fund

Using a new imaging technique to shed light on changes to nerve cells in MND

25 June 201629 April 2022

Reading Time: 2 minutesMagnetic Resonance Imaging (MRI) technology is advancing rapidly as a tool for diagnosing and monitoring disease. In MND, MRI scans are used to understand changes

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Markers of Disease Progression MND Research Research we fund

Using surface EMG to see if fasciculations can be used as a biomarker for MND

24 June 201629 April 2022

Reading Time: 2 minutesWhat are fasciculations? When motor neurones in the spinal cord become damaged this makes them electrically unstable, meaning they spontaneously discharge electrical impulses that cause

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