Reading Time: 2 minutesBiomarkers in Oxford (BioMOx) is a research project with the aim of identifying a diagnostic biomarker for MND, which could be used to track the
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Reading Time: 3 minutesDr Andrea Malaspina is an Association-funded researcher investigating biomarkers, or ‘biological fingerprints’ of MND. Here he blogs about working with patients and basic science. I
Reading Time: 3 minutesYesterday’s announcement by the biotechnology company Trophos SA of the lack of effectiveness of their compound olesoxime adds to the long list of drugs that
Reading Time: 5 minutesPrimary Lateral Sclerosis (PLS) is a type of MND that progress slowly over many years. It is estimated that around 3 in 100 people diagnosed
Reading Time: 6 minutesThis year, we are welcoming our 11th cohort of Non-Clinical Research Fellows to our incredible team of more than 320 scientists involved in research grants
36th Symposium: San Diego Causes and disease mechanisms Events Markers of Disease Progression MND Research Models of MND News Symposium
Bringing the community together for the 36th International Symposium on ALS/MND
Reading Time: 4 minutesThe International Symposium on ALS/MND has closed its doors once again after three insightful, inspiring and hopeful days! After being postponed in 2020 due to the COVID-19 pandemic, we finally made
Reading Time: 2 minutesThe International Symposium on ALS/MND has closed its doors after three insightful, inspiring and hopeful days! This year’s event in San Diego really has showcased the breadth of research happening around the
Reading Time: 2 minutesThe Preclinical and Prodromal ALS session focused on early diagnosis of MND and the use of biomarkers to reveal early signs of the disease. A key approach to this type of research is to use a
Reading Time: 6 minutesMND doesn’t just affect movement – it can also impact thinking and behaviour. Research has suggested that around a third of people with MND also develop changes to their thinking and learning, language and communication and behaviour and emotions. For some people with MND, these changes may be a sign of a type of dementia, known as frontotemporal dementia (FTD).
Reading Time: 7 minutesMND affect cells in the brain and spinal cord, including motor neurons, which connect the brain to the muscles. This makes it challenging to study the disease in people with MND, because researchers cannot take biopsies of cells from brains or spinal cords in the same way that can be done for some other diseases. Therefore, researchers must find other ways of studying MND, such as using cell models in the lab to help to understand disease biology at a microscopic level.