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Correcting the early damage seen in MND

Reading Time: 2 minutes Previous research in humans and zebrafish has shown that before symptoms arise in MND, early changes occur in the interneurones. This type of nerve cell provide a link between the upper and lower motor neurones in the brain and spinal cord. The job of one type of interneurone (called inhibitory interneurones) is to apply the…

From genes to the clinic: MND Association and ALS Association-funded researcher wins the ENCALS Young Investigator Award 2014

Reading Time: 3 minutes After attending the ENCALS meeting in May I was busy scheduling the ‘blog a day’ in June, which meant I didn’t get chance to actually report on any developments from the meeting. During our ‘blog a day’ we wrote a lot about genetics, in terms of the UK MND Whole Genome Sequencing project and the…

The UK Whole Genome Sequencing project

Reading Time: 4 minutes Dr Samantha Price is the Research Information Co-ordinator at the MND Association. As well as organising the ‘blog a day’ during MND Awareness Month she also communicates the latest news about MND research. Here she blogs about the MND Association’s announcement of the UK Whole Genome Sequencing project. It’s been a brilliant Awareness Month with…

MND Researchers: England v Italy

Reading Time: 2 minutes Tonight England will take on Italy in the FIFA World Cup. It’s fair to say England look like they have pretty poor odds of winning the World Cup (yet alone getting through the Group stages!), however I’m sure many England supporters will be cheering on their team tonight as they take on the Italians. As we’re posting…

Physical activity and MND – is there a link?

Reading Time: 5 minutes The results of new research investigating a link between physical activity and MND was presented by the University of Sheffield research group in the late-breaking news session on the last day of the 24th International Symposium on ALS/MND. Under the leadership of Prof Pam Shaw, along with Dr Chris McDermott, MND Association-funded researcher Dr Ceryl Harwood presented…

Same disease.. two very different mice!

Reading Time: 4 minutes The exact course, duration and rate of progression of MND often varies greatly from person to person; even when there is a known family history of the disease caused by a specific MND-causing gene (eg SOD1). This same variability also occurs in mice. Researchers, funded by the MND Association, took two mice with the same SOD1…