Panic at the (Cell’s) Depot

Panic at the (Cell’s) Depot

Reading Time: 5 minutes Guest researcher blog post written by Sam Bryce-Smith – sharing his research into changes in ‘post-code’ sequences of RNA, how it continues during the COVID-19 pandemic, and the importance of his funding. We are extremely grateful for the support of the London Freemasons, who are generously supporting one of our new PhD Studentships held by…

Funding for Gut-sy MND research announced

Reading Time: 3 minutes Yesterday the Reta Lila Weston Trust announced that they will be funding Dr Nikhil Sharma and colleagues at the Leonard Wolfson Experimental Neurology Centre (LWENC) to investigate whether the bacteria that live in our guts could alter the progression of MND. The grant is for £1.2 million over a period of four years. The LWENC…

Toxic proteins may cause motor neurones to die in C9orf72 MND

Reading Time: 4 minutes MND Association and Alzheimer’s Research UK-funded researchers from University College London have identified that toxic proteins may cause motor neurones to die in C9orf72 MND and frontotemporal dementia. Published open access in the journal Science on Thursday 7 August, this research explains more about one of the most common forms of inherited MND.

Structure of C9ORF72 repeat identified by MND Association funded researchers

Reading Time: 4 minutes New exciting findings announced today provide the first insight into the structure and function of a repeated six letter genetic sequence in an MND gene called C9ORF72. Understanding the function of C9ORF72, and how it could go wrong to cause MND, could assist researchers in the future to identify potential treatments that target the disease.…