Reading Time: 6 minutesIt has been suggested that there might be a pre-symptomatic stage of MND, where the disease is active and occurring within a person but no symptoms are showing. There is currently little research in this area and a lack of evidence of a pre-symptomatic stage of the disease. However, if it can be shown that there is a pre-symptomatic stage which can be measured, this could be very useful in helping people with MND to get treatment as early as possible. Dr Michael Benatar, from the University of Miami, has been looking into this by studying the development of MND and how the disease presents in people who have a high risk of developing it.
Category: Symposium
Reading Time: 5 minutesWhat is a clinical endpoint?
A clinical endpoint is used to determine if the drug that is being tested in a clinical trial is beneficial to the people it is intended to treat – those effects that directly measure how a participant in the trial feels, functions or survives.
To determine a clinical endpoint, it is important to understand how a person with a disease feels and functions, and this is well understood in MND. So, a drug that improves any of these could be seen to be beneficial.
33rd Symposium: Virtual Causes and disease mechanisms Healthcare MND Research Research we fund Symposium
Conversations with…4 international MND researchers
Reading Time: 3 minutesLast week at the 33rd International Symposium on ALS/MND, we heard some exciting updates on a wide range of research happening all over the world. The pace of ALS/MND research has drastically increased over recent years and we now have a better understanding about the underlying biology of the disease which is crucial to being able to identify new potential drug targets.
Reading Time: 6 minutesOver the last year ALS/MND clinical trials have taken centre stage, with more trials than ever opening for recruitment in the UK, the news of promising results from some trials and the approval of drugs by some regulatory authorities. With the year coming to an end, we thought we would roundup some recent clinical trial updates that were presented at the 33rd International Symposium on ALS/MND.
Reading Time: 5 minutesThe top-line results of the Modifying Immune Response and OutComes in ALS (MIROCALS) clinical trial were announced on 6 December 2022 at the 33rd International Symposium
Reading Time: < 1 minuteThis blog is part of our Symposium Blogathon series – where we are counting down to the 33rd International Symposium. Numbers in bold blue type correspond
Reading Time: 2 minutesThis blog is part of our Symposium Blogathon series – where we are counting down to the 33rd International Symposium. Throughout November we’ve been counting down
Reading Time: 3 minutesThis blog is part of our Symposium Blogathon series – where we are counting down to the 33rd International Symposium. Numbers in bold blue type correspond
33rd Symposium: Virtual Causes and disease mechanisms Healthcare MND Research Symposium Symposium Blogathon
Symposium Blogathon: Focus on… Diagnosis and Genetic Testing
Reading Time: 3 minutesThis blog is part of our Symposium Blogathon series – where we are counting down to the 33rd International Symposium. Numbers in bold blue type correspond
Reading Time: 2 minutesThis blog is part of our Symposium Blogathon series – where we are counting down to the 33rd International Symposium. Numbers in bold blue type correspond