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Zebrafish show that ‘connector neurons’ are the key in early stages of MND

Reading Time: 3 minutes A recent study by Motor Neurone Disease Association-funded researcher Dr Tennore Ramesh from the Sheffield Institute for Translational Neuroscience (SITraN) has shown that even before the symptoms of MND occur, at the earliest stages of the disease, ‘connector neurones’ known as interneurons are already becoming damaged in the zebrafish. Zebrafish are ideal models for helping…

Vive la difference!

Reading Time: 3 minutes It could be easy to assume that one motor neurone is pretty much like another, but a series of presentations on Thursday clearly showed that we need to be a little more sophisticated in our thinking. Dr Hynek Wichterle (Columbia University) discussed how in the developing embryo, there are distinct regional subtypes of motor neurones…

University of Bath research shows how angiogenin affects motor neurone survival

Reading Time: 3 minutes Published in the prestigious journal Nature Communications and funded by the Wellcome Trust, University of Bath researchers looked closely at the structure of 11 mutated angiogenin proteins, and how changes in their structure influenced activity, function and survival in motor neurones. Dr Brian Dickie, Director of Research at the Association, said “The researchers at the…

Attracting Promising Research – Calling for Project Grant Applications

Reading Time: 2 minutes Autumn is fast approaching which means it’s time to open our online summary application form for our next round of research grant applications. This round is for project grant applications. The deadline for summary applications is Friday 2 November 2012. Reaching out for researchers We currently fund ground breaking projects in a number of would…

X-cell stem cell centre has been investigated by ALS Untangled

Reading Time: 2 minutes With the internet providing an expanse of ‘quackery’ jumbled up with facts, it’s becoming increasingly difficult for anybody to know what source of information can be trusted. This issue is especially apparent to us when we add unproven treatments into the mix. An unproven treatment is, quite literally, a treatment that has no reliable proof for…